Sema-1a Reverse Signaling Promotes Midline Crossing in Response to Secreted Semaphorins
نویسندگان
چکیده
منابع مشابه
Sema-1a Reverse Signaling Promotes Midline Crossing in Response to Secreted Semaphorins.
Commissural axons must cross the midline to form functional midline circuits. In the invertebrate nerve cord and vertebrate spinal cord, midline crossing is mediated in part by Netrin-dependent chemoattraction. Loss of crossing, however, is incomplete in mutants for Netrin or its receptor Frazzled/DCC, suggesting the existence of additional pathways. We identified the transmembrane Semaphorin, ...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2017
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2016.12.027